St. John's Wort Tincture (Hypericum perforatum)

Alcohol-extracted tincture of Hypericum perforatum, St. John's Wort. The tincture format provides concentrated consistent dosing of the herb that has become one of the most-studied modern Western herbs for mood support. The tincture's characteristic red color comes from the hypericin content - the same compound that gives the infused oil its deep red color.

Important Drug Interaction Warning

St. John's Wort has the most extensive list of significant drug interactions of any commonly used herb. The compound hyperforin induces cytochrome P450 liver enzymes, significantly reducing the effectiveness of many prescription medications including: birth control pills, blood thinners (warfarin), HIV medications, transplant rejection medications, chemotherapy drugs, certain heart medications, immunosuppressants. Do not combine with SSRIs or other antidepressants (risk of serotonin syndrome). Do not combine with any prescription medications without consulting a healthcare provider and pharmacist first.

Key Facts

Botanical name

Hypericum perforatum

Format

Alcohol tincture (concentrated liquid extract; characteristic red color from hypericin)

Studied compounds

Hypericin (red color), hyperforin (active for mood and drug interactions), flavonoids

Approved as medicine in

Germany and several European countries (standardized extracts)

Major safety concern

Extensive drug interactions

How to Use St. John's Wort Tincture

Typical use: 30-60 drops in a small amount of water, 1-3 times daily. Effects build over 4-6 weeks of consistent use rather than from single doses. Take consistently for adequate buildup of the active compounds. The tincture is generally taken in the evening or morning depending on individual response.

Frequently Asked Questions

What is St. John's Wort Tincture used for?
Most commonly for mood support, particularly mild-to-moderate mood applications.

Why is it red?
The hypericin content gives the tincture its characteristic deep red color. Same compound that colors the infused oil.

Does it interact with medications?
Yes; the most extensive drug interaction list of any commonly used herb. Consult a healthcare provider before combining with any prescription medications.

Can I combine with antidepressants?
No; risk of serotonin syndrome.

Does it affect birth control?
Yes; significantly reduces effectiveness of birth control pills. Use alternative contraception.

How long until effects build?
Mood support effects typically build over 4-6 weeks of consistent use.

This product has not been approved by the Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. We recommend that you consult with a qualified healthcare practitioner before using any herbal products, particularly if you are pregnant, nursing, or on any medications.